… end stage (ES) HCM population and analyze clinical course and outcome among its different
phenotypes… following clinical features: rare phenocopies including Danon disease, Fabry …

… The clinical presentation and natural history of HCM range … , heart failure (HF) with preserved
ejection fraction (diastolic HF), 3 … Clinical characteristics of the overall HCM cohort and age-…

… still unable to predict phenotypes and outcomes from a gene‐… –related complications peaks
in patients aged 50 to 70 years … to severe end‐stage cardiomyopathy and heart failure in a …

… The most common cause of death was heart failure (HF). … describe the clinical features,
disease stage at presentation and the … Half of patients with classic HCM phenotype died of HCM-…

… clinical profile, prognosis (including risk for heart failure or sudden death), and treatment
strategies for the ES of HCM by revisiting this subset of the HCM disease … range of ages (14 to …

… “Classic” HCM phenotype is defined as the phase in which the hypertrophic phenotype is …
with HCM evolving through the end-stage emerges as that of a young or middle-aged adult (…

… of heart failure-related disability over a wide range of ages. … The clinical presentation and
natural history is particularly … that may result in premature death through several pathways. …

… and IV, or heart failure (HF) or stroke death related to age at initial … In addition, as in coronary
artery disease, endocrine features … of the HCM phenotype or its clinical manifestations (38). …

… with heart failure, disability, and death at any age. In HCM, left … Clinical features of the
study patients were compared with the … The primary clinical end point used in this study was a …

… of clinical manifestations associated with disease progression … of HF, with slow clinical
progression into advanced age. These … Despite the distinct phenotype in these 3 subsets, outcome …